Karamakate used to be the most powerful Shaman in the region, but years of voluntary isolation have drained all memories and emotions from his soul. Evan, an American botanist finds him while seeking the mysterious sacred plant Yakruna. Karamakate gradually awakens as they journey into the impenetrable Amazonian rainforest. Like the converging river current, his forgotten past interweaves with the present, revealing the ill fate of his people, the Cohiuano, and his previous quest for the plant with Theo, a German scientist. Inspired by the journals of the first explorers of the Colombian Amazon in the early 20th century and their austere black & white anthropological photos, this dreamlike pursuit of knowledge is illustrated through spectacular cinematography with the highest respect for the spirit of the jungle and conveys a deeply emotional message.